Some users have claimed MSM supplements have made them gain significant weight which they previously did not have. But, what effects do MSM supplements have on the body? Does it support health like Glucosamine or is any other supplement better? These lead us to the main question: does MSM make you gain weight?

There are no studies to show that MSM supplements make you gain weight. However, you should be aware that all supplements have side effects and that some of these side effects could actually cause weight gain. MSM supplements are available at most health food stores. They contain the highest quality of MSM available on the market today.

About MSM

MSM is a natural, organic sulfur that occurs in many foods, including fruits, vegetables, and grains. It’s also found in some supplements, such as methylsulfonylmethane (MSM).

This supplement is made from organic material that is extracted from food sources and concentrated in a powder for oral consumption. Sulfur is an essential mineral that’s required for many functions within the body, including the production of collagen.

About MSM

Collagen is an important protein that gives structure to connective tissues throughout the body. It’s primarily found in bones, tendons, and cartilage but also plays a role in skin structure and appearance. People use MSM supplements to ease joint pain associated with osteoarthritis and rheumatoid arthritis (RA), treat wounds and injuries, improve skin health and strengthen hair.

4 Reasons MSM Maybe Associated With Weight Gain

Even though there is no concrete evidence to directly link MSM to weight gain, below are some possible reasons why taking MSM supplements can make you gain weight:

1. MSM supplements increase your appetite

If you’ve ever taken a mineral supplement, you might have noticed that you’re hungrier than usual. This is because minerals are involved in many processes of the body and mineral deficiency can lead to a decrease in appetite. One of the key reasons why MSM might be associated with weight gain is because it increases your appetite.

This is a common side effect of many supplements that are meant to help you lose weight. An increase in appetite can cause you to eat more calories than you normally would, which leads to weight gain. But when you take a mineral supplement at the right dose, it can boost your appetite and help you feel more energetic. This is why many people who want to lose weight rely on these supplements.

2. MSM can make you feel bloated

Another reason why MSM might make you gain weight is bloating. Some people also experience diarrhea when taking this supplement and this is another side effect that could make you feel bloated and uncomfortable with your stomach protruding further than usual from your body. This bloating may be due to an increase in gas production which makes it difficult for gases to escape the body easily.

3. MSM may cause Insulin Resistance

MSM might cause weight gain in some people because it can cause insulin resistance. This happens when your body becomes resistant to the effects of insulin and therefore needs more insulin to do its job. Increased insulin levels can lead to fat storage and weight gain.

Insulin is a hormone that’s secreted by the pancreas, and it helps regulate blood sugar levels by causing cells to take up glucose (sugar) from the bloodstream. Insulin resistance occurs when cells have trouble responding to insulin, which causes blood sugar levels to rise. The cells become “resistant” to the effects of insulin and don’t respond as they should.

4. MSM can cause increased Calorie Intake

It’s been suggested that MSM causes increased calorie intake and weight gain because of its effect on ghrelin levels in the body. Ghrelin is known as the hunger hormone because it stimulates appetite by increasing your desire to eat food. When you take MSM for weight loss purposes, your ghrelin levels may increase which may cause an increase in your appetite and cause you to consume more calories than you would without taking MSM supplements.

5 Health Benefits of MSM Supplements

MSM supplements are popular for those who want to support their joints. The benefits of MSM supplements include:

1. MSM supports joints by decreasing joint pain

MSM is most well-known for its ability to support joint health and reduce joint pain. Because MSM contains sulfur (a building block for protein), it’s thought that it boosts collagen production in joints and tissues, enhancing their flexibility and elasticity.

MSM has been widely used as a nutritional supplement for decades because of its numerous health benefits. It supports healthy joint function and helps to maintain normal connective tissue. In fact, many people take MSM supplements to relieve the symptoms of arthritis, osteoarthritis, bursitis, and other joint conditions.

2. Muscle recovery

MSM is a natural anti-inflammatory and antioxidant, which can help to speed up the recovery process after hard workouts or intense exercise. This is because it reduces muscle damage, inflammation, and oxidative stress, all of which are key factors in how long it takes your body to recover.

3. It works for healthy immune functions

MSM is a type of organic sulfur that can be found in all living things, including humans. It’s naturally produced by the body as part of the breakdown process for proteins, but as we age and our bodies become more acidic, we produce less MSM. This combination makes it difficult to maintain healthy immune function and may be one reason why people become more susceptible to colds and cases of flu as they age.

4. It has anti-inflammatory properties

MSM may help reduce inflammation in the body by supporting the production of glutathione, which is a powerful antioxidant that helps protect cells from free radicals. Free radicals can cause oxidative damage to cells, leading to inflammation and other health problems like heart disease and cancer.

5. It supports hormone balance in women

A woman’s hormone balance is very important for her overall health and well-being. As we get older, our hormones begin to fluctuate more than when we were younger. This can cause many problems, including mood swings, water retention, hot flashes, sleep issues, joint pain, and more.

By taking MSM supplements regularly, you may experience an improvement in your hormone balance that helps reduce these symptoms. MSM helps support healthy estrogen levels in women by promoting proper liver function, especially during menopause when estrogen levels naturally decline due to aging or other factors such as stress or lifestyle changes

5 MSM Supplements to Try Out for Weight Loss

Gaining unplanned weight can be disheartening, that is why we recommend these products instead:

1. Jarrow Formulas MSM 1000 mg

Jarrow Formulas MSM 1000 mg - 200 Veggie Caps - Methylsulfonylmethane - Important Source of Organic Sulfur - Strengthens Joints - Up to 200 Servings


Jarrow Formulas MSM 1000 mg is an organic source of bioavailable sulfur, a critical component of healthy cartilage. Sulfur compounds, such as chondroitin sulfate and hyaluronic acid, are found in the body’s structural proteins. This formula contains no allergenic ingredients, artificial coloring or flavoring, yeast, and gluten. Take one veggie capsule one to three times per day with meals or as directed by your healthcare professional.

2. 500mg MSM Organic Sulfur Capsules by No Boundaries Health and Wellness

500mg MSM Organic Sulfur Capsules by No Boundaries Health and Wellness – 180 Vegetable Capsules: No Excipients or Fillers – Premium Health Supplement: 99.9% Pure MSM Powder – Joints, Skin, Hair, Nail


MSM Sulfur is an essential nutrient that has many benefits for overall health and well-being. The Organic MSM Powder can improve hair and nail growth, reduce joint pain and stiffness, stimulate connective tissue production, and detoxify your body. This pure, high-quality organic sulfur capsule is 99.9% pure and tested to ensure you receive the best product possible.

3. Doctor’s Best MSM Powder

Doctor's Best MSM Powder with OptiMSM, Non-GMO, Vegan, Gluten Free, Soy Free, 250 Grams


Doctor’s Best MSM Powder is a high-quality purified MSM (methyl sulfonyl methane) backed by numerous clinical studies for safety and efficacy. It is a natural sulfur compound that helps support the formation of healthy connective tissues. A key component of joint cartilage, MSM also supports overall joint mobility and a normal range of motion. The MSM formula may also help reduce oxidative damage to support a healthy immune system.

4. NOW Supplements

NOW Supplements, MSM (Methylsulfonylmethane) 1,000 mg, Joint Health*, 240 Veg Capsules


The premier sulfur supplement, NOW Sulfur is essential for healthy cartilage and connective tissue. This powerful supplement is vegan, non-GMO, dairy-free, and made without gluten. It’s also certified kosher and vegetarian so you can enjoy it with peace of mind knowing it contains no animal byproducts or any chemical additives.

Providing you with essential sulfur-rich building blocks, this joint supplement helps to maintain flexible joints and healthy connective tissues. This is an advanced formula that contains MSM (methylsulfonylmethane), a naturally occurring organic source of sulfur, proven to support healthy joint cartilage.

5. Kala Health MSM Pure Fine Powder

Kala Health MSMPure Fine Powder, 1 lb, Fast Dissolving Organic Sulfur Crystals, 99% Pure Distilled MSM Supplement, Made in USA


This MSM Pure Fine Powder is 99.9% pure, third-party tested to meet our stringent product specifications. Our MSM Pure goes through a propriety multi-stage distillation process that ensures a 99.9% pure, third-party tested to meet our stringent product specifications.

After years of extensive research, they have developed the best MSM supplement you can buy because they insist on offering only high-quality products formulated to deliver proven results. The powder is highly bioavailable, increasing the amount of inorganic sulfur available for your body to utilize.

In Conclusion

MSM should be purchased from reputable sources, as it’s possible that some manufacturers might try to sell you fake products. Does MSM make you gain weight? No, it doesn’t pose a significant risk for weight gain in healthy individuals when used at the recommended dosage ranges and no side effects have been reported yet.

Disclaimer: This article, other beauty and fashion tips on SheBegan are contributed by experienced fashion professionals, beauty & cosmetics experts. Read our full research and editorial process here. Also, our posts may contain affiliate links, read our full affiliate disclosure

Bisma Farooq is recognized as a top healthcare professional in her country. She is still serving during the pandemic and has won a prestigious medical scholarship award to complete her degree in the medical field. It is our honor to have her here as our guest writer and reviewer of healthcare-related topics.

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